Homologs in FVIII gene
Two molecules, genes, sequences, etc. are said to be homologous when they are derived from a common ancestor. Also known as homologs, these molecules, genes, sequences etc. can be divided into two groups: paralogs and orthologs. Paralogs are homologs that show themselves within one species, and can have differing biochemical functions. Orthologs are homologs that show up in many different species and have very closely related functions. Homology can reveal evolutionary information relating to the molecules, genes, sequences etc., what their function may be or how it has changed [1].
References
[1] Berg, J., Tymoczko, J., & Stryer, L. (2002). Homologs are descended from a common ancestor. New York, NY: WH Freeman. Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK22355/
[2] Homologene, National Center for Biotechnology Information. (n.d.). Retrieved from website: http://www.ncbi.nlm.nih.gov/homologene
[3] BLAST: Basic Local Alignment Search Tool, National Library of Medicine. (n.d.). Retrieved from website: http://blast.ncbi.nlm.nih.gov/Blast.cgi
[2] Homologene, National Center for Biotechnology Information. (n.d.). Retrieved from website: http://www.ncbi.nlm.nih.gov/homologene
[3] BLAST: Basic Local Alignment Search Tool, National Library of Medicine. (n.d.). Retrieved from website: http://blast.ncbi.nlm.nih.gov/Blast.cgi